Constrained thermoresponsive polymers – new insights into fundamentals and applications

• Patricia Flemming,
• Alexander S. Münch,
• Andreas Fery and
• Petra Uhlmann

Beilstein J. Org. Chem. 2021, 17, 2123–2163, doi:10.3762/bjoc.17.138

• physicochemical interplay between the architecture of the polymer assembly and the resulting thermoresponsive switching behavior will be in the foreground of this consideration. Keywords: lower critical solution temperature (LCST); responsive coating; smart material; thermoresponsive polymer; upper critical

• comparison to LCST-based approaches [6][7][59][60][61][62]. However, these reviews and the summarized research papers mainly focus on the application itself. A systematic investigation of the underlying structure–property relationship of the thermoresponsive polymer has only been conducted to a very small

• absolute length of the block copolymer and the relative length of the blocks to each other and the glass transition temperature. If a block is composed of a thermoresponsive polymer, the amphiphilic character and self-assembly ability can be altered by changing the temperature. The thermoresponsive block

Influence of cyclodextrin on the UCST- and LCST-behavior of poly(2-methacrylamido-caprolactam)-co-(N,N-dimethylacrylamide)

• Alexander Burkhart and
• Helmut Ritter

Beilstein J. Org. Chem. 2014, 10, 1951–1958, doi:10.3762/bjoc.10.203

• the use of ROESY-NMR-spectroscopy. Keywords: cyclodextrin; LCST; lysine; 2-methacrylamido-caprolactam; UCST; Introduction Recently, increasing interest has been spent on thermoresponsive polymer solutions, mainly because of their potential application in the field of drug delivery, gene delivery, or

• - and UCST-behavior in water [8]. The TC of a thermoresponsive polymer solution can be altered easily by variation of the chemical structure and to a certain degree by variation of the chain length of the used polymer, also. Interestingly, the TC-values of suitable polymers in water can also be

Hybrid biofunctional nanostructures as stimuli-responsive catalytic systems

• Gernot U. Marten,
• Thorsten Gelbrich and
• Annette M. Schmidt

Beilstein J. Org. Chem. 2010, 6, 922–931, doi:10.3762/bjoc.6.98

• address: Qiagen GmbH Hilden, Germany 10.3762/bjoc.6.98 Abstract A novel active biocatalytic reaction system is proposed by covalently immobilizing porcine pancreas trypsin within the thermoresponsive polymer shell of superparamagnetic Fe3O4 nanoparticles. Active ester-functional nanocarriers suitable for

• of thermodynamic parameters will give more insight to this process. Conclusion In summary the presented results show that the combination of magnetic cores with a biocatalytically active, thermoresponsive polymer shell is a promising approach for nanoscopic carrier systems that allow an external